Nishi Nihon Hifuka
Online ISSN : 1880-4047
Print ISSN : 0386-9784
ISSN-L : 0386-9784
Clinical Case Reports
Three Cases of Erythema Elevatum Diutinum with Hemorrhagic Blisters and Purpura on the Soles
Yoshiaki KUBOHirotsugu TAKIWAKIYoshio URANOHidetaka TSUDAShinji MATSUOSeiji ARASEHiroshi SHIOTA
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1997 Volume 59 Issue 4 Pages 531-535


We herein report 3 cases of erythema elevatum diutinum (EED), consisting of 3 females aged 29, 76 and 81 years old. These patients presented with a variety of skin lesions, such as erythema, purpura, ulcers, and pustules, in addition to the clinically typical plaques and nodules of EED. It seems noteworthy that purpura and hemorrhagic blisters of the soles were found in all cases and developed in one case as the initial lesions. Topical corticosteroids improved the skin lesions in one case while the administration of dapson was dramatically effective in the other 2 cases. In two patients with positive rheumatoid factor, Mooren-type corneal ulcers appeared almost concomitantly with the development of EED, thus suggesting a close relation between the cutaneous and ocular lesions. We therefore conclude that some EED patients might show a wider spectrum of skin lesions than those normally seen in typical cases and as a result, a careful examination of the cornea is therefore recommended in such cases.

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© 1997 by Western Japan Division of JDA
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