We experienced three cases of eosinophilic granuloma with chemotherapy.
Two cases (Case 1 and 3) had single-system multi-site lesion. Case 1 had the lesion in the right thigh and skull. Case 3 had the lesion in the right pelvis, skull, and left 2th rib. We treated them with chemotherapy (JLSG-02) after biopsy.
One case (Case 2) had single-site lesion in the pelvis. We followed him conservatively for one month after biopsy, but the symptoms remained the same. We treated him with chemotherapy (JLSG-02), after which, the lesion tended to decrease.
There are some opinions on eosinophilic granuloma but no consensus. We have had experience of chemotherapy for multi-site and intractable single-site lesions. The clinical outcomes were good.
