A case of multiple schwannoma is reported. A 19-year-old female presented multiple mass in the right femur, right brachium, left palm, right hilum renalis and cauda equina.
Head MR imaging showed bilateral vestibular schwannoma. Histopathological diagnosis of all tumors except the tumor in right hilum renalis and vestibular schwannoma showed the same pattern of Antoni A tissue and Antoni B tissue as schwannoma. Thus this case was diagnosed as neurofibromatosis type 2. There does not appear to be any malignant transformation of neurofibromatosis type 2-related schwannomas. But because of the critical location of many of these tumors in the cranium or spinal cord, patients may succumb to the space-occupying effects of their tumors, and should be carefully observed for a long period.