Familial occurrence of Perthes disease was reported by Hagen in 1939, by Stephens & Kerby in 1964, and by Goff in 1954.
Recently we have observed three brothers with Perthes disease in a family.
The parents of the patients were examined roentgenologically, showing no pathological sign. No evidence has been provided for its hereditary relation and it is suggested, however, that the disease in these three patients may have been related to certain constitutional and hereditary factors.