トリアムシノロン・アセトナイドの局注による断端神経腫の治療

抄録

One-hundred and nineteen post-traumatic neuromas, in thirtyseven patients, were treated by intralesional injection of a solution of triamcinolone acetonide with one percent lidocaine chloride. The tenderness or paresthesia of forty-two neuromas were eliminated after a single injection. Of the forty-eight neuromas was decreased on the twice injections.
The symptoms of eight neuromas failed to respond to triamcinolone injection therapy. Why the triamcinolone injections failed in eight cases is not clear, but these failures may reflect the technical limitation of procedure and failure of the drug to reach the precise location of neuromas. Therapy was less successful for the deeper and the larger neuromas of the arm and the leg.
It suggest that, in the successful cases, the mechanism of relief of the neuroma tenderness is local softening and flattening of scar at the exact neuroma site.
These findings suggest that a trial of this technique prior to surgical treatment on the limbs is given a fair things.