A female, who died at 48 year-old, had been suffering from pain in back, joints and hypochondrium since around 32 years of age. A diagnosis of the tuberculosis of the both kidney was made, and she was admitted to another hospital.
An x-ray examination revealed the gradual increase of radiolucency of the whole bone and the nephrocalcinosis.
Laboratory findings were as follows:
urine…average volume: 2500ml/day,
pH: 6 to 7
specific gravity: 1.010
glucose: negative
protein: 1+reaction
serum…alkaline phosphatase: 30 to 60 King-Armstrong units
inorganic phosphor: 2.1 to 3.4mg/dl etc.
The bone was able to be cut with knife at autopsy.
A case of osteomalacia without specific teratment, presumably caused by renal tubular acidosis, was reported.
