Case 1: A 51 year-old woman visited our outpatient clinic on September 9, 1975 because of swelling and pain in the right knee.
She had experienced abdominal typhoid in 1945. In 1954, she first noticed that her right knee was painful and swollen, and the knee pain lasted thereafter.
On physical examination, her right knee was slightly swollen and local heat and tenderness on the medial condyle of the femur were noticed. Antibiotic therapy was not effective.
She was admitted to our hospital on May 1976 for detailed examination. Laboratory findings were normal except for positive CRP and elevated ESR. On X-ray examination of bone, there were abnormal radiorucent area like Brodie's abscess in the distal end of the right femur.
The pus gained from the cavity showed positive serological test for abdominal typyoid. She has now usual activity of daily living after operation.
Case 2: A 21 year-old woman complained of swelling and pain of the left clavicle since February 1976 and experienced pustulosi palmaris et plantaris on May 1976. Findings of the clavicle were those of the osteomyelitis both radiologically and histologically.
We consider that the osteomyelitis may have some association with the pustulosis palmans et plantaris.