Melorheostosis is a rare systemic bone disease which is characterized roentogeno graphically by hyperostosis and clinically by pain, deformities and limitation of motion of various degree. Its etiology remains obscure in spite of several hypothesis. This report concerns a fourty-eight years female of the disease, complained of pain and palpable defotimy of right radius. Histological examination showed extremely dense bone and derangement of Haversien systemes. By bone scanning with 99mTc pyrophosphate, high accumulation of it located on right forearm. The possibility of existence of the imflammation was discussed.