Clinical data of 180 cases (794 examinations) of definite or classical rheumatoid arthritis were analysed statistically and discussed on the correlation with between immunoglobulin (IgG, IgA and IgM) and joint symptoms.
IgG has increased in cases with heavy joint symptoms, and decreased according to anti-inflammatory effect by treatment.
IgA has also increased in cases with heavy joint symptoms, but not allways decreased by treatment.
It is noteworthy that many of the cases showing constantly high titer of IgA are often suffering from contructures of multiple joints.
In cases which IgM showed more than 300mg/dl joint symptoms were heavy.
