A 71-year-old male had onset of pain in the sacral region about 10 years ago. A part of tumor found in the sacral region was diagnosed on biopsy as a chordoma, surgically removed and treated with irreadidtion but the symptoms did not disappear. The patient died 8 years after biopsy. Post-mortem autopsy disclosed that metastasis was found in the lungs, the pleura, …etc.
The histological examination revealed that in the early sample lobular arrangements of the large vacuolated or physaliphoroas tumor cells were found, and in the late sample, anaplastic spindle cells were presented.