1984 年 32 巻 2 号 p. 365-369
Thirty patients (31 locations) with pathologic fracture from metastatic cancer were treated with internal fixation supplemented by methylmethacrylate. Primary organs involved were breast (16), lung (6), kidney (3), liver (2), maxillary sinus (1), esophagus (1), and uterus (1). The most frequent location of pathologic fracture was the femoral shaft which occurred in 64.5% of 31 locations. The internal fixation of pathologic fractures offers many advantages. Pain usually disappears within a few days and freed from external fixation. Seventy-three percent had excellent or good results and in only three results were poor. In one patient the postoperative complication (DIC) occurred and two had deterioration of general condition. All but three patients benefited from the procedure in terms of pain relief, improved mobility, and ease of nursing care. The use of methylmethacrylate as an adjuvant in internal fixation of pathologic fractures and postoperative radiation appeared to be the best treatment.