Clinical usefullness of the bone-scintigraphy with 99mTc-MDP was evaluated. Of 131 patients studied from 1979 to 1982, a high percentage of positive uptake was observed in cases of primary malignant bone tumor, metastatic bone tumor, tumor-like bone lesion, fracture, osteomyelitis and aseptic osteonecrosis. As to primary malignant bone tumor, an extent of the local involvement may be better defined. In metastatic bone tumor, distribution of the tumor may be observed cleary. As to bone infection, early bone involvement can be demonstrated before roentgenographic changes are detected. In bone necrosis, living area may be detected.
