We previously reported that synthesized eel calcitonine and 1α25(OH)2D3 each promote calcification in the widened growth plate in cases of EHDP induced rickets in the healing stage. In this experiment, in order to evaluate whether hypercalcemia contributed to the calcification observed in this model, calcium gluconate was administered to Fisher female rats with EHDP induced rickets. Calcium gluconate enhanced the calcification in the epiphyseal growth plate. This mode of calcification was like that of 1α25(OH)2D3.
