We report a few cases of compression of dorsal root ganglia. The dorsal root ganglion normally lies within the lateral portion of the intervertebral foramen and is not directly compressed by a bulging disc prolapse or a bony spur which may compromise the nerve root. This ganglion contains cell bodies of first-order sensory neurons. The chemical response to mechanical deformation of the dorsal root ganglion may hold significance for some of the unknowns in the etiology of low-back pain.