1992 年 41 巻 1 号 p. 174-176
In a previons study we found that the motor nerve conduction velocity in humans was delayed in a low pressure environment (510mmHg). We have how investigated the nerve blood flow of anesthetized rabbits in a low pressure environment.
Rabbits were anesthetized by intramuscular administration of ketamine (80ng/kg) and xylazine (8mg/kg) and then the sciatic nerve blood flow was measured using the laser doppler flowmeter and systolic blood pressure in the femoral artery measured.
Systolic blood pressure and even more notably, the of rabbits were significantly reduced in the low pressure environment. There was significant correlation in both measured values.
These results suggest that reduction of nerve blood flow possibly causes the delay of motor nerve conduction velocity.