Five patients with malignant musculoskeletal tumors who had pathologic fractures after radiation therapy were studied clinically. All patients had osteoporotic changes at the irradiation site before being fractured. The pathologic fractures occurred from 2 to 8 years after irradiation. One patient was treated with gyps fixation, one with plating, three had intramedullary nailing. Three patients who were treated by plating or intramedullary nailing developed bone union, but this took more than one year. Non-union occurred in two patients who received more than 80Gy irradiation.
Intramedullary nailing is a useful method for treatment of pathologic fractures after irradiation.