1993 年 42 巻 4 号 p. 1536-1539
Calcified material taken from a seventy-year-old female patient with calcification in the ligamenta flava of the cervical spine was analyzed crystallographically and ultrastructurally by electron probe microanalyzer (EPMA).
Rod-shaped crystals of 0.5-3μm in diameter were recognized on the upper side, and round shaped crystals of 1-7μm in diameter were found on the lower side of the ligament flava at the same intervertebral level. These crystals were identified as calcium pyrophosphate dihydrate and hydroxyapatite, respectively. At the transitional zone, each crystal coexisted individually in a mosaic pattern. No intermediate form of the crystal was noted.
There is a possibility that both crystals coexist primarily, instead of a structural alteration of the crystals.