Mega-dose chemotherapy and peripheral blood stem cell transplantation was performed on a case of Ewing's sarcoma of the pelvis. A 13-year-old male was admitted with fever and left buttock pain. Tumor was found to occupy the left wing of the ileum on CT. The tumor demonstrated small round cells with positive PAS staining cytologically. After radiotherapy and normal-dose chemotherapy, he received megadose chemotherapy consisting of carboplatin, etoposide and ifosfamide and stored peripheral blood stem cells were transplanted. Rapid hematological recovery was observed with few complications. He had been well for 2 months until the tumor relapsed in the same area.
