Nippon Shokakibyo Gakkai Zasshi
Online ISSN : 1349-7693
Print ISSN : 0446-6586
Case Report
A case of ulcerative colitis refractory to intravenous cyclosporine therapy successfully treated with infliximab
Ryosuke TSUYASatoshi MOTOYAHiroki TANAKASuguru NAKAGAKIHitoshi NISHIOKATakeshi HAGIWARAHiroshi KOZAWASei KUROKAWATomonori AMBOAkimichi IMAMURA
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2008 Volume 105 Issue 5 Pages 679-685

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Abstract

A 26-year-old woman was admitted to our hospital with relapse of ulcerative colitis (UC). We diagnosed it as a refractory UC because intravenous corticosteroid therapy had no effect. Intravenous cyclosporine therapy and other conventional therapies did not lead to remission. Then the possibility of infliximab was discussed with the patient and her parents and treatment with infliximab was started. Infliximab was infused intravenously at a dose of 5mg per kilograms of body weight. Immediately after the first infusion, clinical symptoms improved, and clinical remission was achieved within 12 weeks. It is suggested that infliximab can be effective for refractory UC.

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© 2008 by The Japanese Society of Gastroenterology
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