肝生検が診断の契機となった肝Mycobacterium avium complex症の1例

疋田 健人; 高見 史朗; 杉本 博子; 木村 英憲; 田中 順子; 中島 潤; 寄木 浩行; 城 正泰; 全 圭夏; 益澤 明; 松本 尚之; 若林 直樹; 片岡 慶正; 益澤 尚子

doi:10.11405/nisshoshi.115.818

Case report

A case of liver Mycobacterium avium complex syndrome, diagnosed by liver biopsy

Kento HIKITA, Shiro TAKAMI, Hiroko SUGIMOTO, Hidenori KIMURA, Noriko TANAKA, Jun NAKAJIMA, Hiroyuki YORIKI, Masayasu JO, Keika ZEN, Akira MASUZAWA, Naoyuki MATSUMOTO, Naoki WAKABAYASHI, Keisho KATAOKA, Naoko MASUZAWA

Author information

Kento HIKITA
Department of Gastroenterology and Hepatology, Otsu City Hospital
Shiro TAKAMI
Department of Gastroenterology and Hepatology, Otsu City Hospital
Hiroko SUGIMOTO
Department of Gastroenterology and Hepatology, Otsu City Hospital
Hidenori KIMURA
Department of Gastroenterology and Hepatology, Otsu City Hospital
Noriko TANAKA
Department of Gastroenterology and Hepatology, Otsu City Hospital
Jun NAKAJIMA
Department of Gastroenterology and Hepatology, Otsu City Hospital
Hiroyuki YORIKI
Department of Gastroenterology and Hepatology, Otsu City Hospital
Masayasu JO
Department of Gastroenterology and Hepatology, Otsu City Hospital
Keika ZEN
Department of Gastroenterology and Hepatology, Otsu City Hospital
Akira MASUZAWA
Department of Gastroenterology and Hepatology, Otsu City Hospital
Naoyuki MATSUMOTO
Department of Gastroenterology and Hepatology, Otsu City Hospital
Naoki WAKABAYASHI
Department of Gastroenterology and Hepatology, Otsu City Hospital
Keisho KATAOKA
Department of Gastroenterology and Hepatology, Otsu City Hospital
Naoko MASUZAWA
Department of Pathology, Otsu City Hospital

JOURNAL FREE ACCESS

2018 Volume 115 Issue 9 Pages 818-824

DOI https://doi.org/10.11405/nisshoshi.115.818

Details

Abstract

A man in his 70s was referred to our hospital for evaluation of low-grade fever, weight loss, and liver dysfunction. Serological tests for viral hepatitis or autoimmune diseases were negative. No significant findings were observed on whole-body computed tomography (CT). Histopathologic examination of a liver biopsy sample revealed a non-caseating granuloma with acid-fast bacillus using the Ziehl-Neelsen stain. Serum Mycobacterium avium complex (MAC) antibody was positive. We started treatment for pulmonary MAC disease. His clinical condition and liver function improved within two months. He was diagnosed with liver MAC disease.

Corresponding author

Register with J-STAGE for free!