Pancreatitis in Patients with Pulmonary Tuberculosis

Abstract

In 65 patients complaining of digestive symptome among 100 cases of pulmonary tuberculosis observed between April 1964 and desember 1966, the tender points of pancreatic disease Kudo) and various pancreatic function tests were studied. Further detailed clinicla studies were carried out in those who showed abnormalities. Following results were obtained.
1) In 65 patients complaining of digestive symptoms among 100 cases of pulmonary tuberculosis, agreement of both tender points of pancreatic disease and endocrine and exocrine function tests of pancreatic function was seen in 32 cases, representing 32% of patients with pulmonary tuberclosis and 51.6% of patients with digestive complaints. Frequent occurrence or pancreatitis in pulmonary tuberculosis was sugested.
2) An exellent agreement between tender points of pancreatic desease and endcrine and exocrine pancreatic function test might indicate the clinical value of tender points of pancfcatic desease in the diagnosis of pancreatitis.
3) In the relationship between abnormalities in pancreatic disease and antituberculosis preparation, disturb ance in pancreatic function was more frequently found in patients given
PAS than in those without PAS treatment, indicating a significant difference.
4) In 10 of the patients with abnormal pancreatic function, pancreozymin-secretin test was carried out to determine the amount of pancreatic secretion, maximum concentration of bicarbonate, total amylase concentration, and amylase output. Lower values than in controls were encountered in 9.
5) Clniical examination in patients with abnormal pancreatic function revealed, cases stomach in gastric fluorescopy, anacidity or hypoacidity in gastric analysis, abnormalities in liver function was seen in 18.8%, and hypocalcemia in a few cases. In cholecystography and examination of the duodenal juice, complication of cholecystopaty was frequently noted, suggesting the profound relationship of cholecystopaty on pancreatitis in patients with pulmonary tuberculosis.