各種胃疾患の胃液内電解質に関する研究

抄録

Patients with gastric diseases were divided into the group of gastric cancer, gastric ulcer and duodenal ulcer, on one hand, and the group of atrophic gastritis, diagnosed by the gastrocamera, on the other. Electrolytes in the gastric juice were studied on these cases, comparing with those of the normal subjects.
Sodium, potassium and chlorine concentrations were compared with one another in the gastric juice of basal secretion, as well as in the gastric juice obtained 30 minutes and 120 minutes after injection of augumented histamine dose.
In cancer of the stomach, sodium concentration was found to be highest, showing gradual decrease in the order of gastric ulcer, duodenal ulcer, and normal.
About potassium, the concentration was slightly lower in cancer of the stomach, and no remarkable increase was shown in chlorine concentration of gastric cancer.
In atrophic gastritis, sodium concentration was higher in proportion to the severity of at-tophic changes. While potassium and chlorine concentration showed reversed tendency.
The ratio of Na/K was highest in gastric juice of cancer of the stomach and showed gradual decrease in order of gastric ulcer and duodenal ulcer, and also showed gradual increase in proportion to the severity of atrophy. Na/Cl ratio was statistically higher than other gastric deseases and normal at 30 minutes after injection of histamine.
In conclusion, it was statietically proved that Na/K and Na/Cl ratio in cancer of the stomach was significantly higher in comparison with the other diseases.