日本消化器病学会雑誌
Online ISSN : 1349-7693
Print ISSN : 0446-6586
胃癌組織における Leucine aminopeptidase の組織化学的研究およびその胃癌細胞診への応用
後篇 酵素化学的染色の胃癌細胞診への応用
原 久弥
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1970 年 67 巻 6 号 p. 438-456

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16 kinds of enzymes were cytochemically examined for the purpose of application to cytochemical diagnosis of gastric cancer.
They are Alkaline phosphatase (ALP), Acid phosphatase, Leucine aminopaptidase (LAP), Esterase, 5'-Nucleotidase, β-Glucuronidase, phosphorylase (PR), Lactic dehydrogenase, Malic dehydrogenase, Glutamic dehydrogenase, Succinic dehydrogenase, Glucose-6-phosphate dehydrogenase, lsocitrate dehydrogenase, NADdiaphorase (NADd) and Monoamine Oxidase.
The resutts show efficiency of combined methods of three enzymatic staining, LAP, ALP and NADd, as well as PR.
This finding was applied to the cytology of 100 cases of gastric cancer. Both cytochemical and cytomorphological diagnosis compensate each weak point's with total diagnostic results attaining to 100%.

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