1970 年 67 巻 6 号 p. 438-456
16 kinds of enzymes were cytochemically examined for the purpose of application to cytochemical diagnosis of gastric cancer.
They are Alkaline phosphatase (ALP), Acid phosphatase, Leucine aminopaptidase (LAP), Esterase, 5'-Nucleotidase, β-Glucuronidase, phosphorylase (PR), Lactic dehydrogenase, Malic dehydrogenase, Glutamic dehydrogenase, Succinic dehydrogenase, Glucose-6-phosphate dehydrogenase, lsocitrate dehydrogenase, NADdiaphorase (NADd) and Monoamine Oxidase.
The resutts show efficiency of combined methods of three enzymatic staining, LAP, ALP and NADd, as well as PR.
This finding was applied to the cytology of 100 cases of gastric cancer. Both cytochemical and cytomorphological diagnosis compensate each weak point's with total diagnostic results attaining to 100%.