Nippon Shokakibyo Gakkai Zasshi
Online ISSN : 1349-7693
Print ISSN : 0446-6586
Studies on Large Tapeworm
Part 3. Tareatment of large tapeworm infections in man. (Taenia saginata and Diphyllobothrium latum)
Tsuyoshi KIHARARiyoichi KOBAYASHIOsamu TSUJISatoru OKAZAKIKiyowo KOSAKA
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Keywords: Niclosamide
JOURNAL FREE ACCESS

1973 Volume 70 Issue 3 Pages 196-207

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Abstract

In spite of a number of reports on the side effect of aspidium, it's misbelieved generally that most reliable and effective drug for the expulsion of tapeworms is aspidium. But the treatment of tapeworm by aspidium is empirical, often inefficient, not uncommonly dangerous and toxic to the host.
Since 16 years, the authors tried the various anthelminthics and the physical expulsive method on 50 patients harbouring Taenia saginata and 13 patients harbouring Diphyllobothrium latum (Table 4, 5). As a result of the treatments, niclosamide is most effective and safety in elminating large tapeworms from the the human intestinal tract. But niclosamide should not be used in Taenia solium infections because of the increased risk of cystocercosis.
Damaso De Rivas reported in 1932 the physical expulsive method of intestinal parasitism and in this report, he applied a transduodenal irrigation with hot physiological salt solution at a temperature in the duodenum of between 45°to 47°C. But according to the authors' animal experiments, the authors may infer that this hot physiological salt solution is injurious to the rat duodenal mucosa (Fig. 2, 3, 4, 5, ). The authors modified this method and applied the hot pysiological salt solution at a temperature in the duodenum of 42°C. The authors tried this modified method of Damaso De Rivas on 5 patients with beef tapeworm and 2 patients with broad tapeworm and all cases discharged a long stroblia with scolex after the transduodenal irrigation. This modified physical expulsive method, when properly applied, has been proven to be effective and free from toxic side effects and secondary complications. (Table 6).

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© The Japanese Society of Gastroenterology
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