Absorption of glucose from the stomach; Preliminary report

Abstract

Absorption of glucose from the stomach with intestinal mataplasia was studied by double sampling method instilling 300ml of 5% or 10% glucose solution for 20 minutes. Forty eight subjects were examined in this study.
Rate of glucose absorption from the stomach was neither related closely to extent of intestinal metaplasia, nor to gastric emptying.
As the brush border of intestinal metaplasia contains many kinds of disaccharidase reported by Sugimura, it is possible to think that glucose may be absorbed from the gastric mucosa with intestinal metaplasia.
In our study of 48 cases with intestinal metaplasia of the gastric mucosa, 21 cases showed the results suggesting gastric absorption of glucose much or less. Rate of glucose absorption from the stomach ranged a few % to 48% of instilled glucose in those 21 cases.