アミラーゼアイソザイムによる高アミラーゼ血症の臨床的解析 シアール酸結合型マクロアミラセミアと思われる1症例をふくむ

富士 匡; 河村 奨; 清水 道彦; 有山 重美; 東 光生; 前谷 昇; 中村 克衛; 竹本 忠良; 原田 善雄; 阿美古 秀美; 岩武 忠昭; 久保 勝彦

doi:10.11405/nisshoshi1964.75.1062

CLINICAL STUDY ON HYPERAMYLASEMIA DUE TO THE ANALYSIS OF AMYLASE-ISOENZYME

Tadasu FUJI, Susumu KAWAMURA, Michihiko SHIMIZU, Shigemi ARIYAMA, Mitsuo AZUMA, Noboru MAETANI, Katsue NAKAMURA, Tadayoshi TAKEMOTO, Yoshio HARADA, Hidemi ABIKO, Tadaaki IWATAKE, Katsuhiko KUBO

Author information

Tadasu FUJI
First Department of Internal Medicine, Yamaguchi University School of Medicine
Susumu KAWAMURA
First Department of Internal Medicine, Yamaguchi University School of Medicine
Michihiko SHIMIZU
First Department of Internal Medicine, Yamaguchi University School of Medicine
Shigemi ARIYAMA
First Department of Internal Medicine, Yamaguchi University School of Medicine
Mitsuo AZUMA
First Department of Internal Medicine, Yamaguchi University School of Medicine
Noboru MAETANI
First Department of Internal Medicine, Yamaguchi University School of Medicine
Katsue NAKAMURA
First Department of Internal Medicine, Yamaguchi University School of Medicine
Tadayoshi TAKEMOTO
First Department of Internal Medicine, Yamaguchi University School of Medicine
Yoshio HARADA
Department of Internal Medicine, UBE Industries, Ltd., Central Hospital
Hidemi ABIKO
Department of Internal Medicine, UBE Industries, Ltd., Central Hospital
Tadaaki IWATAKE
Department of Internal Medicine, UBE Industries, Ltd., Central Hospital
Katsuhiko KUBO
Department of Internal Medicine, UBE Industries, Ltd., Central Hospital

Keywords: macroamylasemia

JOURNAL FREE ACCESS

1978 Volume 75 Issue 7 Pages 1062-1068

DOI https://doi.org/10.11405/nisshoshi1964.75.1062

Details

Abstract

Since last year, we have experienced 29 cases with hyperamylasemia and studied on amylaseisoenzyme pattern in their sera.
According to this study, 26 out of 29 cases showed something different pattern from the normal controls, in the meaning of"P"dominant or"S"dominant.
We found out 2 cases with macroamylasemia in these 29 cases and concluded biochemically one was IgA complex and the other was sialic acid complex.
Particullary, the case of macroamylasemia due to amylase-sialic acid complex seems to be rare.
Anyway, the analysis of the case with hyper and macroamylasemia must be very significant in the relationship between pancreatic diseases and hyperamylasemia.

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