STUDY ON DISACHARIDASE ACTIVITY OF BIOPSY SPECIMES

Part 1: especially on duodenal bulb

Abstract

We observed duodenal bulb by endoscopy, and measured disaccharibdase (maltase, lactase) activity of biopsya specimens by gaschromtography.
(1) Disaccharidase activity was influenced by the weight of biopsy specimens and larger weight showed olwer activity and smaller showed higher.
(2) There were no sifference of activity by sex and age.
(3) Both maltase and lactase activit showed high value in intact duodenal bulb, and maltase was clearly lower in surrounding duodenal ulcer and duodenal ulcer scar (focus) than in intact duodenal bulb. Lactase was lower in surrounding focuses than in intact duodenal bulb, but was same in the part of 1.5cm-2.0cm from focuses (unfocus) as in intact duodenal blb.
(4) Regarding to fluctuation of activity in each stage of duodenal ulcer, maltase was high in both stage H₂ of surrounding focuses and unforcuses, and lactase had no difference by stage and part.
(5) Observing the distribution of villi form of uodenal bulb by stereoscopic microscopy, finger type villi occupied many part of it in intact duodenal bulb, surrounding facuses and ulfocuses. It was highest in intact duodenal bulb andhigher in duodenal ulcer scar than in duodenal ulcer.
(6) In each type of villi, maltase and lactase were high in finger type of intact duodenal bulb an low in big leaf type and ridge type.
(7) Regarding to fluctuation of disaccharidase activity in each stage of duodenal ulcer, maltase was high in stage H₂ and Sl finger type villi and low in big leaf type and ridge type of each stage.