CORRELATION BETWEEN ENDOTOXEMIA AND ENDOSCOPIC FINDINGS OF ESOPHAGEAL VARICES

with special reference to hemorrhage

Abstract

1) 75% of cases with persisting endotoxemia had episodes of hemorrhage and 50% of them was shown to have the Stage 3 of esophageal varices.
2) Only 4.7% of cases without endotoxemia had episodes of hemorrhage and most of them were shown to have the Stage 1 and 2 of esophageal varices.
3) The postoperative prognosis of cases with persistent endotoxemia was poor. On the other hand, in the cases without endotoxemia or, in which endotoxemia disappeared by Lactulose or Kanamycine, their postoperative prognosis seemed to be good. It is, thus, suggested that endotoxemia is one of the important factors to infuluence the postoperative course, and the preoperative treatment with Lactulose or Kanamycine against endotoxemia is essential before the surgery.
4) It was found that 53.8% of cases with endotoxemia had upper gastro-intestinal lesions such as erosion or peptic ulcer, which was significantly frequent compared with 23.8% of cases with no endotoxemia having these lesions.