Nippon Shokakibyo Gakkai Zasshi
Online ISSN : 1349-7693
Print ISSN : 0446-6586
THE EFFECT OF PANCREATIC JUICE DIVERSION ON PLASMA SECRETIN LEVEL AND PANCREATIC SECRETION IN POSTPRANDIAL STATE IN DOGS
Hideki NISHIWAKIKatsusuke SATAKEKaoru UMEYAMAW.Y. Chey
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1981 Volume 78 Issue 7 Pages 1459-1465

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Abstract

The effect of pancreatic juice diversion from the duodenum on plasma secretin level and pancreatic secretion after meal ingestion were investigated in 5 dogs with pancreatic fistula and gastric canula.
Exclusion of pancreatic juice resulted in a mean peak secretin level of 80.6±18.2 pg/ml and 8.3±1.7 ng/ml/150 min. of integrated scretin response for 150 minutes after meal ingestion; this coincided with a significant increase in pancreatic volume and bicarbonate out put. However, reinfusion of the collected pancreatic juice decreased the response of secretin secretion; a mean peak level of 57.0±15.0 pg/ml and the integrated secretin secretion of 5.0±0.8 ng/ml/150 min, which was acompanied by a decrease in pancreatic volume and bicarbonate output.

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© The Japanese Society of Gastroenterology
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