1983 Volume 80 Issue 12 Pages 2485-2492
A pathological study on stomach and esophageal wall was carried on 11 autopsy cases after endoscopical sclerotherapy. The following conclusion was obtained.
1. The most of the cases have severe histological damage on esophageal wall, characterized by deep and wide ulceration, necrosis, hemorrhage, extensive inflammatory cell infiltrate to adventitia associated with an occasional mediastinitis. These changes were more striking in the cases with the sclerotherapy by Paoscle.
2. Thrombogenesis in varices was observed in a wide range. This was considered to be related to the degree of the histological damage rather than the amount of the injected sclerosant. In some cases thrombosis was sufficiently formed by less amount of the sclerosant.
3. Further studies on the more cases with sclerotherapy including long-term survival cases will reveal the exact application for sclerotherapy.
Nippon Shokakibyo Gakkai Zasshi
Nippon Shokakibyo Gakkai Zasshi Kou
