Nippon Shokakibyo Gakkai Zasshi
Online ISSN : 1349-7693
Print ISSN : 0446-6586
NUTRITIONAL STUDY IN THE AREA WITH HIGH INCIDENCE OF LIVER CIRRHOSIS AND HEPATOCELLULAR CARCINOMA IN JAPAN
Tatsuo MUNEHISAKeisuke NAKATAKenji KONOToyokichi MUROAkira SATORyuji FURUKAWAYukio KUSUMOTOShigenobu NAGATAKINobuko ISHIIToshihiko KOJIToshie NUGUISHIMichiko KIMURANoriko KIMURA
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1983 Volume 80 Issue 3 Pages 828-836

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Abstract

A nutritional survey was carried out in Tomié-Town, Goto Islands, Nagasaki Prefecture where the incidence of both liver cirrhosis and hepatocellular carcinoma has been the highest in Japan.
Analysis on 143 inhabitants of Tomié-Town revealed that their daily intake of total calories, protein, fat, calcium, vitamin A, B1, B2 and C was lower than the averages of nutritional intake in whole Japanese population. Furthermore, constitution of their food was different from that of average Japanese population and was the nutritionally disproportional pattern.
When the results in these inhabitants were compared between patients with clinical and/or biochemical liver damage and healthy controls, or between hepatitis B antigen carriers and the others, low nutritional intake and abnormal food constitution correlated closely with liver diseases.
These results suggest that although it is not clear whether the undernutrition causes the high incidence of chronic liver diseases or chronic liver diseases are the cause of the undernutrition, nutritional intake is inadequate and unbalanced in the patients with chronic liver diseases even when they are spending normal life without any complaints.

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© The Japanese Society of Gastroenterology
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