1983 Volume 80 Issue 3 Pages 851-856
To determine whether standard liver function tests reflect histological severity of alcoholic liver diseases, 93 patients were evaluated with liver biopsy and the results by a multiple regression analysis of standard liver function tests were compared with liver histology.
The best combination of standard liver function tests to distinguish between various types of alcoholic liver diseases was the combination of γ-globulin, GOT/GPT ratio, GPT and total alcohol intake. Using these parameters, the probability to discriminate liver cirrhosis and alcoholic hepatitis from various types of alcoholic liver diseases was 64% and 75%, respectively.
The best combination to distinguish liver cirrhosis from liver fibrosis was the combination of γ-globulin, total alcohol intake and Al-P. The probability of the discrimination between liver cirrhosis and liver fibrosis was 76%-79%.