ELECTRON MICROSCOPIC OBSERVATION ON THE PANCREAS AFTER THE EXPERIMENTAL LIGATION OF THE COMMON BILE DUCT IN RATS

Abstract

The present examination has been attempted to investigate morphological changes of pancreatic acinar and islet cells after complete ligation of common bile duct in rats using electron microscope.
At the early stage of the ligation of the common bile duct (2nd weeks after the ligation), the most of acinar cells and B cells of the Langerhans islands showed hyperfunctional appearance, but no remarkable changes were observed in the A cells. At the late stage (4th weeks after the ligation), acinar cells became atrophied and B cells were degenerative changes, however many of A cells showed hyperfunctional appearance.