Nippon Shokakibyo Gakkai Zasshi
Online ISSN : 1349-7693
Print ISSN : 0446-6586
SERUM PANCREATIC SECRETORY TRYPSIN INHIBITOR (PSTI), AMYLASE ACTIVITY AND PANCREATIC ISOAMYLASE ACTIVITY IN PANCREATIC DISEASES
Itsuo SUEHIROMakoto OTSUKITohru OKAYoshiinori OKABAYASHIAtsushi OHKITsutomu KANDAHosai YUUMitsuo MAEDATomio YAMASAKIShigeaki BABA
Author information
JOURNAL FREE ACCESS

1984 Volume 81 Issue 4 Pages 1044-1049

Details
Abstract

Pancreatic secretory trypsin inhibitor (PSTI) in serum from patients with pancreatic diseases was measured by using the recently developed method of radioimmunoassay and compared these results with serum amylase ativity in the same sample. Serum PSTI concentration in 25 healthy subjects was 10.7±2.7ng/ml (mean±SD). All the patients with acute pancreatitis had an elevated serum PSTI concentration, which remained at the elevated level for several days even after serum amylase activity has returned to normal range. On the other hand, elevated serum PSTI concentration decreased to the normal range earlier than serum amylase activity in patients who showed an elevation of serum amylase activity after secretin stimulation. However, serum PSTI concentration in patients with chronic calcifying pancreatitis was not different from that of normal persons. These results suggest that serum PSTI concentration correlates with the severity of acute pancreatitis, but not with that of exocrine pancreatic insufficiency.

Content from these authors
© The Japanese Society of Gastroenterology
Previous article Next article
feedback
Top