PATHOHISTOLOGICAL ANALYSIS OF GASTRIC CARCINOMA ACCOMPANIED WITH PEPTIC ULCER

Abstract

Of 759 gastric carcinomas found in 679 surgically resected stomachs, 131 lesions (17.3%) were accompanied with peptic ulcer. The associated peptic ulcer was significantly common in the gastric carcinoma which was grossly depressed typed early gastric carcinoma or depressed typed early carcinoma-like advanced carcinoma, histologically undifferentiated type, and located in an intermediate area. Peptic ulceration tended to occur at the invasive portion of submucosal or more advanced gastric carcinomas, and it is supposed as one of the reasons why the gastric carcinoma showing malignant cycle grows slowly. A contiguous type peptic ulcer showing F1 or F2 phase fibrosis is suggested to be a peptic ulcer occurring secondarily at the invasive portion of gastric carcinoma.