2010 Volume 69 Issue 6 Pages 347-351
A 38-year-old female was referred to our hospital with proteinuria. She had exhibited a urinary abnormality for the past 16 years since she was 22 years of age. She was diagnosed with IgA nephropathy of the good prognosis group based upon histological examination. Therefore, she was not treated at that time except for undergoing tonsillectomy for prevention of focal tonsillar infection. After 16 years, she was again reported due to her continuous proteinuria. A second biopsy revealed advanced IgA nephropathy without indication of glucocorticoid treatment. This evidence suggests that tonsillectomy alone was not sufficient to regulate the progression of IgA nephropathy but might mask the progression of glomerulonephritis.