2010 Volume 69 Issue 6 Pages 370-373
A 66-year-old man with advanced cervical esophageal carcinoma and lymph node swelling of the neck underwent neoadjuvant chemoradiotherapy with 5-FU/CDDP. Primary tumor and lymph node swelling revealed remarkable responsiveness to chemoradiotherapy. The esophageal carcinoma disappeared and an irregular mucosal membrane was observed by endoscopy. Radical resection was performed in consideration of residual cancer at the cellular level. A free jejunal graft was used for reconstruction following removal of the pharynx, larynx, and cervical esophagus. Pathologic examination of the resected specimens revealed no malignant cells in the esophagus and lymph node. In this case, preoperative chemoradiotherapy was clearly effective for esophageal carcinoma.