Journal of Nihon University Medical Association
Online ISSN : 1884-0779
Print ISSN : 0029-0424
ISSN-L : 0029-0424
Special Articles:
Regulation of Regulatory T Cell and B Cell Target Therapies
Sumiko Kobayashi
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Keywords: B cell target, rituximab (anti-CD20 monoclonal antibody), ANCA-associated vasculitis, regulatory T cell, immune response
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2017 Volume 76 Issue 1 Pages 11-14

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Abstract

Recent studies have shown that depletion or reduction of regulatory T cells can improve advanced solid tumors. It is expected this new field will lead to enhancement of immune responses against tumor mass. By contrast, B cell target therapies, such as anti CD20 monoclonal antibody treatment using rituximab or other new antibody agents, have also been developed for auto immune diseases.

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© 2017 The Nihon University Medical Association
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