脳と発達
Online ISSN : 1884-7668
Print ISSN : 0029-0831
ISSN-L : 0029-0831
点頭てんかんの病因に関する研究
脳波学的, 生化学的検討
児玉 荘一瀬尾 明根岸 宏邦荻野 仁志伊坂 稔
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1973 年 5 巻 1 号 p. 59-67

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The children with infantile spasms (West's syndrome) were studied electroencephalographycally and bioc, hemically.
1) Forty-four percent (8 of 18 cases) of infantile spasms, most of which showed no response to the ACTH-Z treatment, changed into the Lennox syndrome.
2) Tn 8 of 18 cases, the electroencephalographic pattern changed from hypsarhythmia to 2 c/s spike nd wave pattern.
3) The cases of infantile spasms with a history of perinatal injuries were associated with cerebral palsy in high percentage.
4) The 5-hydroxyindolacetic acid (5-HIAA) level in lumbar cerebrospinal fluids of these patients with Lennox syndrome is low (29-56 ngm/ml) in comparison with that of the other neurological patients (45-82 ngm/m/).

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