1973 年 5 巻 1 号 p. 59-67
The children with infantile spasms (West's syndrome) were studied electroencephalographycally and bioc, hemically.
1) Forty-four percent (8 of 18 cases) of infantile spasms, most of which showed no response to the ACTH-Z treatment, changed into the Lennox syndrome.
2) Tn 8 of 18 cases, the electroencephalographic pattern changed from hypsarhythmia to 2 c/s spike nd wave pattern.
3) The cases of infantile spasms with a history of perinatal injuries were associated with cerebral palsy in high percentage.
4) The 5-hydroxyindolacetic acid (5-HIAA) level in lumbar cerebrospinal fluids of these patients with Lennox syndrome is low (29-56 ngm/ml) in comparison with that of the other neurological patients (45-82 ngm/m/).