A case of subacute sclerosing panencephalitis (SSPE), 12-year-old boy was reported. The exactdate of measles infection was not known but said to be around 2 to 4 years of age. About 10 yearslater, he developed indifference to the surroundings followed by myoclonic seizures. He had mentalretardation since infancy but it became more marked prior to the onset of these symptoms.
EEG findings showed changes with the course of the disease and became gradually typical withperiodic high voltage burst. He had extraordinary high levels of measles antibody titers both in serumand CSF. He also had high IgG level in CSF though his IgG level in serum remained normal. Heshowed positive delaped skin reaction against purified measles antigen but negative result against Schwartz live vaccine. Thymus biopsy revealed the evidence of old inflammation suggesting that thepatient had some immunological abnormalities.
