1984 Volume 47 Issue 3-4 Pages 123-129
It was found that no effect of increase in dermal blood flow depended solely on HCO3- or CO32-, but on CO2 gas dissolved in water.
The artificial CO2 bath was prepared with sodium bicarbonate and citric acid, mixing simply in plain water at 38-40°C.
Thermal efficacy was confirmed by a rise in temperature of oral, finger tip and forehead respectively, and by a high transepidermal water loss (TWL) in consequence of increase in dermal blood flow, compared to a plain bathing.
A remarkable effect in artificial CO2 bathing of 400-800ppm has been well-known clinically, however, a substantial increase in dermal blood flow has observed with artificial CO2-bathing of 59.8ppm or greater in this study, so that a CO2-bathing using the preparation would be popularized.