Research resources bank of Ministry of Health and Labor was established in 1984. Our bank has accumulated a lot of know-how while providing research resources to many researchers. Especially with regard to the ethical handling on human-derived sample, is large role that public bank plays. Recently, we have been able to build a system that supplies in a refrigerated state, such as fresh human synovial tissue in Japan. Besides this, we are aggressively prepared to provide a sample prepared in the cells from the tissue. The future it can be expected that these know-how becomes the foundation for the regenerative medicine.