腫瘍部位マーカーと光計測技術を用いた手術ナビゲーションシステム

抄録

To construct minimal invasive navigation in real time, we introduce optical measurement techniques with tumor sensitizer, which are 2-Color Photo-Dynamic Diagnosis (2C-PDD), Near Infrared Fluorescence Computed Tomography (NIR-FCT) and 2-Color Optical Coherence Dosigraphy (2C-OCD). Applying 2C-PDD to navigation system of brain tumor, one can obtain high contrast images between tumor lesion and normal tissue. To detect a tumor site deeply located, we employ NIR-FCT and construct fluorescence computed tomography images by convolution back projection method. To detect infinitesimal tumor, we develop a functional optical coherence tomography, namely 2C-OCD, which enables to visualize both the scatterer density and drug concentration.