鼻副鼻腔悪性腫瘍の臨床統計

吉村 知倫; 大原 浩達; 芦澤 圭; 中山 雅博; 廣瀬 由紀; 中馬越 真理子; 西村 文吾; 星野 朝文; 田中 秀峰; 上前泊 功; 村下 秀和; 田渕 経司; 大久保 英樹; 和田 哲郎; 原 晃

doi:10.11453/orltokyo.56.s49

A CLINICAL STUDY OF MALIGNANCIES OF THE NASAL CAVITY AND PARANASAL SINUSES

Tomonori Yoshimura, Hirotatsu Ohara, Kei Ashizawa, Masahiro Nakayama, Yuki Hirose, Mariko Nakamagoe, Bungo Nishimura, Tomofumi Hoshino, Shuho Tanaka, Isao Uemaetomari, Hidekazu Murashita, Keiji Tabuchi, Hideki Okubo, Tetsuro Wada, Akira Hara

Author information

Tomonori Yoshimura
Department of Otolaryngology, University of Tsukuba Hospital
Hirotatsu Ohara
Department of Otolaryngology, University of Tsukuba Hospital
Kei Ashizawa
Department of Otolaryngology, University of Tsukuba Hospital
Masahiro Nakayama
Department of Otolaryngology, University of Tsukuba Hospital
Yuki Hirose
Department of Otolaryngology, University of Tsukuba Hospital
Mariko Nakamagoe
Department of Otolaryngology, University of Tsukuba Hospital
Bungo Nishimura
Department of Otolaryngology, Faculty of Medicine, University of Tsukuba
Tomofumi Hoshino
Department of Otolaryngology, Faculty of Medicine, University of Tsukuba
Shuho Tanaka
Department of Otolaryngology, Faculty of Medicine, University of Tsukuba
Isao Uemaetomari
Department of Otolaryngology, Faculty of Medicine, University of Tsukuba
Hidekazu Murashita
Department of Otolaryngology, University of Tsukuba Hospital
Keiji Tabuchi
Department of Otolaryngology, Faculty of Medicine, University of Tsukuba
Hideki Okubo
Department of Otolaryngology, Faculty of Medicine, University of Tsukuba
Tetsuro Wada
Department of Otolaryngology, Faculty of Medicine, University of Tsukuba
Akira Hara
Department of Otolaryngology, Faculty of Medicine, University of Tsukuba

Keywords: malignancies of the nasal cavity and paranasal sinuses, preoperative radiation therapy, intraarterial chemotherapy, multidisciplinary treatment, survival rate

JOURNAL FREE ACCESS

2013 Volume 56 Issue Supplement1 Pages s49-s53

DOI https://doi.org/10.11453/orltokyo.56.s49

Details

Abstract

The data of a total of 82 patients with malignancies of the nasal cavity and paranasal sinuses who were initially treated at the University of Tsukuba Hospital between 2002 and 2011 were reviewed. The mean age (±standard deviation) was 63.1 (±14.6) years, and the male-female ratio was 2.73: 1. The tumor originated from the maxiallry sinus in 40 cases (48.8%), from the nasal cavity in 28 cases (34.1%), from the ethmoid sinus in 9 cases (11.0%), and from other sinuses in 5 cases (6.1%).
At our department, treatment for maxillary cancer is initiated with chemoradiotherapy concurrently with intraarterial infusion of fluorouracil, followed by planned surgery for appropriate candidates. The disease-specific 5-year survival rate was 57.0% in our series of patients with maxillary cancer.
Malignancies of the nasal cavity and paranasal sinuses may present with diverse clinical features and further investigation is needed to establish appropriate treatment strategies for individual cases.

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