耳鼻咽喉科領域疾患治療上の側面

主としてアレルギー性因子をめぐつて

抄録

In otorhinolaryngology, diseases related to allergy are not few. Yet this fact has of ten failed to be reminded in our day to day practice.
A certain allergic element is responsible for tinnitus, hearing hardness, forlign feeling of the pharynx and throat, vertigo, headache (frontal headache, bilateral frontal headache, visual abnormality, nausea, vomitting and throbbing pain can be caused by allergy), or the allergy plays a part during the disease process.
History taking is quite important. Detail quetioning not infrequently points the responsible allergen.
Allergic reaction is a chain of events; first it starts with combination of the antigen to the antibody, a certain enzyme system is activated, cells are damaged, their impairment promotes liberation of the activated substances such as SAS-A from the mast cells. The antigen is single, but can be multiple at times.
Desensitization requires a long period and is impossible occasionally.
“Intensified Minophagen C” acts inhibitive on the antibody production, the antigenantibody reaction and tissue reactions.
The intensified Minophagen C reportedly works on relatively wide portions of the allergic reaction. It effects on the reticuloendothelial function and appeared to influence on phagocytosis and the anti-allergic actions.
Following two points should be reminded during an inspection for diagnosis;
1) capillary dilatation of the cheeks.
2) pale face and tender skin.
The capillary dilatation (either congenital or aquired, the dilatation is considered to be related to abnormal functions of the autonomic nervous system and endocrine system) and its relation to the allergy are now under inves tigation.