The purpose of this study is to investigate the contractility of the nasal mucous membrane in the presence of epinephrine and the hypersensitiveness of the nasal mucous membrane towards acetylcholine in patients with nasal allergies. Comparative investigations were also conducted between the above subjects and subjects with normal nasal mucous membranes by measuring the nasal breathing resistance in order to detect whether it is a useful measuring tool in diagnosing hypersensitivity of the upper respiratory tract.
The results of this investigation revealed that there was a significant difference in the rise of nasal breathing resistance in the acetylcholine induced nasal mucous membrane tests between normal patients and those with nasal allergies. However, a test investigating the contractility of the nasal mucous membrane through epinephrine spraying failed to differentiate between the nasal allergy and the normal nasal mucous membrane.
