耳鼻咽喉科展望
Online ISSN : 1883-6429
Print ISSN : 0386-9687
ISSN-L : 0386-9687
副鼻腔炎に対する薬物療法
実験的副鼻腔炎に対するCarbocisteineの効果
前山 拓夫大山 勝松根 彰志小川 和昭深水 浩三飯田 冨美子大堀 八州一内薗 明裕松永 信也上野 員義今給黎 泰二郎宮崎 康博田渕 えり子田中 和代片平 聖子
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1986 年 29 巻 Supplement6 号 p. 447-457

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Efficacy of Carbocisteine in experimental sinusitis in rabbits was evaluated in the morphological and biochemical study. Observations through the light and scanning electron microscopy revealed a marked improvement in sinusitis in the group of rabbits treated with Carbocisteine comparing with those in the control.
Degrees of the improvoment tended to increase in a dose response manner.
Biochemical research showed that the serum level of L-fucose in the groups treated with Carbocisteine was lower than that of the nontreated group.
Based on the results mentioned above, Garbocisteine is considered to be one of the useful drugs for sinusitis.
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