1989 年 32 巻 6 号 p. 557-561
The effect of menthol on the nose was examined in this study.
On inhalation of menthol, “chilling”, “clearing” and “refreshing” sensations, which were followed by the sensation of increasing nasal airflow, were experienced by five of the normal subjects.
Even though the changes in nasal airflow sensation were as described above, none of the subjects demonstrated significant change in respiratory resistance through the nose. Thus, menthol had no effect on respiratory resistance through the nose. As noted above, menthol appeared to stimulate the sensory fibers of normal nasal mucosa inducing the change in sensation. These changes in nasal airflow sensation were less noted in the patients with nasal allergy or chronic sinusitis with nasal polyps, probably because the environment surrounding the nerve endings of the nasal mucosa is different from that of the normal subjects. It can be stated that the sensation of increasing nasal airflow is not necessarily in agreement with a decrease in nasal resistance through the nose.