The therapeutic effect of the high-dose steroids was investigated in 7 cases of sudden deafness with a profound hearing loss and the result was compared with that of 14 cases with a profound hearing loss treated by the ordinary therapeutic protocol. The steroids were administered by the modified Stennert's protocol.
There were no clear differences in the outcome of hearing loss between these groups. However, the rapid recovery of the hearing loss was observed immediately after the administration of the high-dose steroids in 2 cases which showed no clear recovery by the prior treatment with Urokinase®.
The leucocytosis and elevation of serum GOT and GPT were found in more than half of the cases which could be the side effects of administration of the high-dose steroids and Molecular Dextran L®. However, these side effects disappeared rapidly after the administration was completed.
