慢性GVHD患者に生じたMedial Meatal Fibrosisの一例

抄録

We experienced a case of medial meatal fibrosis, which is a rare entity linked to inflammatory and traumatic factors. A 25-year-old woman suffered from hearing loss in both ears. She had developed graft-versus-host disease (GVHD) following bone marrow transplantation for the treatment of chronic myelogenous leukemia 7 years ago. As a sign of GVHD, she had had chronic external otitis for 4 years, and her hearing had deteriorated gradually. On otoscopic inspection and computed tomographic examination, the tympanic membranes were found to be thickened and lateralized, but no abnormalities were observed in the middle ears in both sides. She underwent meatoplasty bilaterally. After removing the postinflammatory connective tissue in the external ear canal and thickened lamina propria, the raw surfaces were covered with skin grafts. Postoperatively, the hearing became normal, and no recurrence had been observed for 2 and half years.